Oligonucleotide synthesis
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence.
Oligonucleotides must be of high purity when used in molecular biology applications, but efficient purification over a large range of production scales is challenging. The Gilson GX-271 Oligonucleotide Purification System provides a versatile solution for continuous separation, analysis, and desalting of oligonucleotides.
The GX-271 Oligo Purification System is a single liquid handling platform configured with automated preparative and analytical HPLC capabilities that can be used to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run.
Синтез олигонуклеотидов – это химический синтез относительно коротких фрагментов нуклеиновых кислот с заданной химической структурой (последовательностью). Метод применяется в современной лабораторной практике для получения олигонуклеотидов нужной последовательности быстрым и недорогим способом.
Синтез олигонуклеотидов в значительной степени автоматизирован, установка синтеза олигонуклеотидов (GX-271 Oligo Purification System)